Couple of questions

[The Archivist]

1) Interaction between Lonewolf and Premiere Leon with active level 2 ability:
-Lonewolf applies to each explore. Does the damage bonus also apply each time a weapon is used within the same explore? i.e. If Lonewolf granted +20 damage to a Handgun (30 damage total) and that weapon is used twice, are we looking at 60 total damage for that explore?

2) Power of the t-Virus in partner mode:
-Is it +20 damage for the turn to one character or both? Some of the other single effects (i.e. Wasp) are easy to interpret, but this one is a little funky because +40 damage would be a huge swing

3) Medic skill levels 2 and 3 with Symbol of Evil and GENCON Wesker:
-This is an effect layering question. If your character has damage on him at the beginning of the turn, I'm assuming you can resolve these effects however you choose. i.e. draw a card from Wesker's ability, take damage and draw the card for Symbol, then heal using the medic skill, then trashing a card. Clearly you can't trash without healing first. I had this come up in a game with Promo Wesker with two Symbols of Evil attached and medic Level 3. This amounted to four beginning of turn triggers. It mattered because I wanted to be able to trash a card before my discard pile was reshuffled because of the other draws. Jeez.

4) Osmund Saddler in partner mode:
-Is that punk handing out 6x "ammo x10's" for two characters with active level 2 abilities that can't take him down?

[135forte]

1) The Blowback Pistol raised the same question and apparently never got an official ruling, but I would think that it applies to both uses.
3) The general opinion seems to be that you can pick the order the effects trigger but you must resolve one before going to the next.

Sadly, for 2 and 4, only the Alliance cards are made to interact with Partners, so it pretty much comes down to what your group decides unless you can find a definitive answer, such as what was given for the Nightmare Hunter. That said, I would have Saddler's effect work off of the highest level Character you have and just pick one Character to get the Power of the T-Virus's effect.

[The Archivist]

1) The Blowback Pistol raised the same question and apparently never got an official ruling, but I would think that it applies to both uses.
3) The general opinion seems to be that you can pick the order the effects trigger but you must resolve one before going to the next.

Sadly, for 2 and 4, only the Alliance cards are made to interact with Partners, so it pretty much comes down to what your group decides unless you can find a definitive answer, such as what was given for the Nightmare Hunter. That said, I would have Saddler's effect work off of the highest level Character you have and just pick one Character to get the Power of the T-Virus's effect.

Sounds reasonable to me. Thanks for the input!

[Khrest]

2) Power of the T-Virus does state "Your Character' so i can only imagine it is talking about one. 40 damage for one infection seems pretty obscene for a 20 gold event card.

[Khrest]

4) It says the "Exploring Character". I would say the character you chose to lead the assault in would be the Exploring Character even though they are both exploring.
I'm sure that's how you calculate The Wisp or Rocket Launcher Militia's effect as well.

The Reaper is the only other Infected that actually states "Players Main Character's Partner" in any text, all others either state "all characters" or "Exploring Character".

[Khrest]

1) Both the Blowback Pistol and the Lonewolf card say the damage stays until the >end of this turn. They apply to both uses (as a side note the Burst-Fire Handgun also says until "end of this turn". It would actually deal 20+20 damage on the first use, then 20+20+20 on the second use. High priority to NOT let Premier Leon get this

[135forte]

That is because Alliance, which the Reaper came from, is the only expansion prior to Mercs that had rules for Partners and most likely will still be the only one with cards for it. All other sets have to be modified to work with the Partner rules.