Originally Posted by Hikari Link
I did misread your statement. I'll agree it is more likely, but still probably won't happen. As for Tsunade dying, I'm not so sure. She's already getting on in years and Naruto is pretty near the point of being Hokage, so there doesn't need to be any sort of death or intermediate period. I could easily see Tsunade handing over her position to Naruto. I guess she could get killed by Kabutorochimaru, but maybe not. Maybe she'll finally show her hidden skill and kill him.
But before Naruto is ready to become Hokage, Tsunade's death will occur. She's already used Milotic Regeneration at least twice, and each uses shortens her life span. The Leaf isn't big on handing the reigns to the village to young ninjas, no matter how powerful. Namikaze was the youngest, and he was still closer to thirty.