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This would not be a great battle because it would never happen. Kisame and Itachi are partners, and more in fangirl minds. But just pretending it would happen, I'm inclined to say Kisame would win, because I like Kisame, and the Uchiha's suck. But in all honesty, I think, it would all come down to who is physically stronger because they know each others powers and weaknesses because they are partners. Itachi is lightweight and would be fast, but (spoiler) He's loosing his eyesight, so he wouldn't be able to tell very well where Kisame was. Now Kisame is big and slow so he might not be able to catch Itachi. But, since they know each others strengths and weaknesses, I think Kisame would win.
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